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Cornell University

Fischbach Lab

We apply engineering principles to understand how tissue microenvironments influence cancer initiation, development, and therapy response.

News

August 07, 2023

Matt and Siyoung’s recent paper in Nature Biomedical Engineering has been featured in the Cornell Chronicle!

July 10, 2023

Congrats to Garrett Beeghly for being awarded a Ruth L. Kirschstein National Research Service Award (F31) from the National Cancer Institute!

June 27, 2023

Congratulations to Regan Stephenson for successfully defending her dissertation on microenvironmental regulation of tumor-associated macrophages. Way to go Regan!

May 09, 2023

Congrats to Adrian Shimpi for defending his thesis! Adrian will be starting a post doc at the University of Virginia with Dr. Kristen Naegle.

April 27, 2023

Yiwei and Logan presented their research at the Cornell Engineering Learning Initiatives (ELI) poster session. Way to go!

Feb 27, 2023

Congratulations to Matt Tan for successfully defending his thesis! He will be moving to the University of Michigan to start his post-doctoral position with Dr. Claudia Lobel.

Dec 16, 2022

Congrats to Garrett for receiving the Caroline Coffey Fund Travel Award to attend the 2023 Gordon Research Conference on the Physical Science of Cancer.

Dec 09, 2022

Shola passed her Admission to Candidacy Exam. Congratulations to our newest PhD candidate!

Nov 21, 2022

Matt Whitman and Shola’s proposal to the Cornell Institute of Biotechnology Seed Grant Award Program was selected for funding. Way to go Matt and Shola!

Oct 21, 2022

Congratulations to Brittany for coming in third place in the rapid-fire research presentation contest at the Society for Women Engineers’ Annual Meeting.

Oct 18, 2022

Congratulations to Claudia for receiving an inaugural Cornell EPICC Award for her commitment to sustaining collaboration between Cornell Engineering and Weill Cornell Medicine.

Aug 26, 2022

Regan was awarded a National Institute of Biomedical Imaging and Bioengineering (NIBIB) T32 Immunoengineering Training Grant. Congrats Regan!

Apr 05, 2022

Kylie was awarded the National Science Foundation (NSF) GRFP Fellowship. Congrats Kylie!

Feb 04, 2022

Garrett’s review article has been published in Annual Review of Biomedical Engineering. This review was written in collaboration with Sanjay Kumar at University of California, Berkeley.

Nov 10, 2021

Kylie, a first-year PhD student in the Meinig School of Biomedical Engineering, has joined the lab. Welcome Kylie!

Jul 21, 2020

Aaron and Lu have successfully defended their PhDs. Aaron will begin a postdoc at Stanford University and Lu will start a postdoc at University of California, Berkeley. Congratulations to Aaron and Lu!

Jul 01, 2020

Dr. Fischbach has been elected as the inaugural Stanley Bryer 1946 Professor of Biomedical Engineering. Congrats Claudia!

May 28, 2020

Aaron’s manuscript “Fluorescent silica nanoparticles to label metastatic tumor cells in mineralized bone microenvironments” has been published in Small.

Apr 07, 2020

Matt Tan has been awarded a $25,000 research initiative grant from the Breast Cancer Coalition of Rochester to support his thesis. Congratulations Matt!

Oct 31, 2019

Nora has successfully defended her thesis and is now faculty at Kansas State. Congratulations!

Oct 20, 2019

Aaron and Matt Whitman both received Young Investigator Awards at the International Conference on the Chemistry and Biology of Mineralized Tissues (ICCBMT). Congrats!

Oct 10, 2019

Want to know more about the research that we do and our interactions with the local cancer community in Ithaca? Check out a research spotlight featuring Garrett!

Oct 04, 2019

Check out Garrett’s clinical immersion term spotlight!

Sep 20, 2019

Matthew Tan’s poster presentation “Investigating the effect of metabolism and the perivascular niche on cancer stem cell properties” received an award at the Physical Sciences Oncology Network (PS-ON) Annual Investigator’s Meeting. Congrats Matt!

Sep 09, 2019

Garrett has been featured in a video about the Cornell Community Cancer Partnership!

Jul 16, 2019

Nora’s manuscript “Obesity-associated extracellular matrix remodeling promotes a macrophage phenotype similar to tumor-associated macrophages” has been published in The American Journal of Pathology. Congratulations to Nora!

Jun 21, 2019

Michael’s manuscript “Endothelial cells promote 3D invasion of GBM by IL8 dependent induction of cancer stem cell properties” has been published in Scientific Reports!

May 15, 2019

Claudia’s perspective “The Physics of Cancer” has been published in Cancer Research. Articles in collaboration with the Estroff Lab and Cerione Lab have also been published with work by Aaron and Lu. See our publication page for more details.

Apr 29, 2019

Garrett Beeghly was awarded the National Science Foundation (NSF) GRFP Fellowship. Congrats Garrett!

Aug 08, 2018

Frank has successfully defended his thesis. Michael and Jane’s paper “Collagen fiber alignment alters endothelial network formation in 3D hydrogels” has been published. Congratulations!

May 23, 2018

Peter’s review article with the Cantley Lab “Cancer metabolism gets physical” has been published in Science Translational Medicine. Congrats Peter!

May 01, 2018

Siyoung’s paper “Intrafibrillar, bone-mimetic collagen mineralization regulates breast cancer cell adhesion and migration” has been accepted for publication in Biomaterials.

Apr 15, 2018

Aaron has received a National Institutes of Health (NIH) F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award. Way to go Aaron!

Apr 03, 2018

Brittany Schutrum and Matthew Whitman have both been awarded the National Science Foundation (NSF) GRFP Fellowship. Congratulations Brittany and Matt!

Mar 10, 2018

Joe’s review “Biophysical properties of extracellular matrix: Linking obesity and cancer” has been published in Trends in Cancer. Congrats to Joe!

Feb 05, 2018

Bianca’s paper “CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling” has been accepted for publication in Integrative Biology. Congratulations Bianca!

Oct 25, 2017

Peter DelNero and Alexandra McGregor (Lammerding Lab) describe their efforts (in Science Translational Medicine) to promote dialogue with cancer patients as an important element of preclinical research.

Oct 21, 2017

Our lab participated in the annual walkathon and 5k for the Cancer Resource Center of the Finger Lakes. Together, we were able to raise more than $3,800 to provide free services to people in our community affected by cancer.

Aug 28, 2017

Jane Wei has been chosen to receive a 2017 Biomedical Engineering Society (BMES) Student Design and Research Award! She will receive the award at the annual BMES meeting on Oct 13, 2017 in Phoenix, Arizona. Congrats Jane!

Aug 23, 2017

Frank’s paper “Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis” has been accepted for publication in PNAS. Associated Cornell Chronicle article on this project

Apr 25, 2017

Matthew Tan has been awarded a Graduate Assistantship in Areas of National Need (GAANN) Fellowship from the US Department of Education to help develop a new undergraduate lab course in the Meinig School of Biomedical Engineering.

Mar 18, 2017

Adrian Shimpi and Matthew Tan have been awarded the National Science Foundation (NSF) GRFP Fellowship and NSF GRFP Honorable Mention, respectively. Congratulations Adrian and Matt!

Jan 13, 2017

Peter DelNero has been awarded the Patricia Cross Future Leaders Award for 2017. Congratulations to Peter!

Sep 01, 2016

A new NIH U54 grant co-directed by Claudia and Lew Cantley at Weill Cornell Medicine launches the Center on the Physics of Cancer Metabolism.

Jun 01, 2016

Young Hye has successfully defended her thesis and is now starting as a postdoctoral researcher in the Schmidt Lab at the University of Florida. Congratulations!

Feb 26, 2016

Peter DelNero received a Cornell Engaged Graduate Student Grant and a Buttrick-Crippen Fellowship to enhance public awareness and communication related to cancer. Congratulations!

Jan 26, 2016

Claudia was elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). Congrats Claudia!

Oct 24, 2015

Our lab participated in the 2015 walkathon and 5k for the Cancer Resource Center of the Finer Lakes to help raise funds for people in our community who face cancer.

Sep 28, 2015

Aaron was awarded a Graduate Assistantship in Areas of National Need (GAANN) Fellowship from the US Department of Education to help develop a class for BME undergraduate students at Cornell.

Sep 18, 2015

Claudia’s op-ed on Missing the Soil for the Seeds in Cancer Research was published in Scientific American.

Aug 19, 2015

Science AAAS News featured Bo Ri’s new paper on the role of obesity-induced matrix stiffness in breast cancer that was published in Science Translational Medicine.

Feb 23, 2015

Claudia has written an op-ed on the need for collaborative research between engineers and cancer biologists.

Aug 26, 2014

Bo Ri has successfully defended her thesis and Maureen’s review on “Biomechanical forces in the skeleton and their relevance to bone metastasis: Biology and engineering considerations” has been accepted in Advanced Drug Delivery Reviews. Congratulations to Bo Ri and Maureen!

Mar 26, 2014

Claudia has been invited to serve as a permanent member on the National Institutes of Health (NIH) Tumor Microenvironment (TME) Study Section.

Oct 08, 2013

David’s paper “Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche” has been accepted in Cancer Research. Congrats to David!

Aug 12, 2013

Bo Ri won best poster at the Biomaterials and Tissue Engineering Gordon Research Conference and Maureen was runner-up for postdocs at the same meeting. Allie, a summer REU student, has received a BMES Student Travel Award. Congratulations to all!

Jul 09, 2013

Claudia has been awarded a fellowship for experienced researchers by the Alexander von Humboldt Foundation in Germany. This fellowship will allow her to conduct a one-year research project in the Department of Biomaterials at the Max Planck Institute of Colloids and Interfaces in Potsdam, Germany where she will collaborate with Dr. Peter Fratzl to evaluate the role of bone materials properties in breast cancer bone metastasis.

Mar 29, 2013

Michael McCoy received a prestigious National Science Foundation (NSF) GRFP Fellowship. Congratulations to Michael!

Mar 28, 2013

Several manuscripts have been accepted for publication recently, check out our publications page for more details.

Mar 19, 2013

We held the first Fischbach Lab retreat at LaTourelle Resort. There was lots of great science and fun!

Sep 14, 2012

Maureen has received a travel grant from the International Bone and Mineral Society to attend the 12th International Conference on Cancer-Induced Bone Disease in Lyon, France. Congrats!

Sep 14, 2012

Peter’s abstract for the SFB Annual Fall Meeting has received a STAR award and Frank has been awarded a Howard Hughes Medical Institute Med-into-Grad Fellowship. Congratulations to both Peter and Frank!

Jun 15, 2012

Congratulations to Emily for successfully defending her PhD thesis!

Jun 06, 2012

Emily’s and Bo Ri’s paper “Implanted adipose progenitor cells as physicochemical regulators of breast cancer” has been published in PNAS. Congratulations!

Apr 02, 2012

Both Frank He and Peter DelNero received prestigious National Science Foundation (NSF) GRFP Fellowships. Congratulations!

Jan 03, 2012

We wish Dr. Scott Verbridge all the best as he begins his new position as an Assistant Professor of Biomedical Engineering at Virginia Tech.

Jan 03, 2012

Youjin has received an undergraduate research award from the Cornell Engineering Learning Initiative. Congratulations!

Nov 04, 2011

Maureen has been selected to receive a prestigious postdoctoral fellowship from the Hartwell Foundation. Congrats!

Oct 05, 2011

Two new PhD students, Peter DelNero and Frank He, have joined the lab. Welcome Peter and Frank!

Oct 05, 2011

Young Hye has received a MOGAM Fellowship from South Korea and Kelsey has been awarded an undergraduate research fellowship from the Cornell Engineering Learning Initiative. Congrats to both!

Jul 26, 2011

Two new NIH R21 grants from the NCI will support our projects “Mineralized 3D tumor models to study breast cancer bone metastasis” and “Fibronectin and its role in tumor stiffness and vascularization.”

Jul 01, 2011

David has received a two-year Research Fellowship from the American Brain Tumor Association. Congrats David!

Mar 22, 2011

Siddharth’s and Debra’s (Estroff Lab) joint paper on “Hydroxyapatite nanoparticle-containing scaffolds for the study of breast cancer bone metastasis” has been accepted for publication in Biomaterials. Congratulations!

Mar 22, 2011

Brian Kwee, an undergraduate in the lab, has won the first-place prize at this year’s Bioexpo poster competition.

Jan 19, 2011

Emily’s paper entitled “Stiffness of photocrosslinked RGD-alginate gels regulates adipose progenitor cell behavior” has been accepted in Biotechnology and Bioengineering. Congratulations!

Dec 14, 2010

Emily’s paper “Adipose progenitor cells increase fibronectin matrix strain and unfolding in breast tumors” has been accepted for publication in Physical Biology. Congrats!

Dec 14, 2010

Congratulations to Bo Ri for being awarded a prestigious MOGAM Scholarship from South Korea.

Nov 05, 2010

Bo Ri’s poster was awarded the third-place prize at this year’s Cornell Stem Cell Symposium. Congratulations!

Oct 18, 2010

Congratulations to Maya for receiving an award from the NASA/New York Space Grant Consortium for Undergraduate Early Science and Engineering Research and to Iriny for being awarded an undergraduate research grant from the Cornell Engineering Learning Initiative.

Sep 14, 2010

Two new PhD students, Young-Hye Song and Ryan Nolan have joined the lab. Welcome!

May 27, 2010

Brian and Jimmy, undergraduate researchers in the lab, have received awards for the summer. Brian received the Cornell Engineering Learning Initiatives Grant and Jimmy received the New York State Stem Cell Grant. Congratulations!

May 10, 2010

Siddharth has passed his A exam and is now officially a PhD candidate. Congratulations!

Mar 18, 2010

Jimmy and Christine, undergraduates in the lab, have won second and third place at this year’s BioExpo. Congratulations!

Mar 17, 2010

Emily has been selected for a STAR award from the Society for Biomaterials for her work “Tumor microenvironmental cues signal host tissue progenitor cells to promote tumorigenesis” which will be presented at the 2010 Annual SFB Meeting in Seattle. Congratulations!

Mar 09, 2010

Scott’s and Emily’s review article on “Tissue-engineered 3D tumor models to study tumor angiogenesis” has been accepted for publication in Tissue Engineering.

Mar 09, 2010

Scott’s and Nakwon’s article on “Oxygen-controlled 3D cultures to analyze tumor angiogenesis” has been accepted for publication in Tissue Engineering.

Jan 08, 2010

Siddharth’s paper “A novel 3D mineralized tumor model to study breast cancer bone metastasis” has been accepted in PLoS ONE. Congratulations!

Oct 30, 2009

Claudia will lead one of the projects of the recently funded NIH PSOC at Cornell. This center will apply physical science approaches to advance research on cancer.

Oct 22, 2009

David Infanger, a new postdoctoral researcher, has joined the lab. Welcome David!

Oct 14, 2009

Claudia will be the lead PI on an NIH RC1 grant to collaborate with Ithaca and Weill Cornell researchers on “Microfluidic tumor models to analyze the role of physicochemical cues in the angiogenic switch.”

Oct 14, 2009

Emily has received the second-place prize at the poster competition for the Cornell Annual Stem Cell Symposium.

May 06, 2009

Ramya has been awarded a fellowship by the Cornell Engineering Learning Initiative for her proposed summer project on biomineralized culture systems to study bone metastasis. Congratulations Ramya!

Apr 10, 2009

Siddharth, a second-year PhD student in the lab, has been awarded a National Science Foundation (NSF) GRFP Fellowship for his work on engineered bone metastasis models. Congrats to Sid!

Apr 10, 2009

Ramya, an undergraduate researcher in the lab, has been recently featured in the Cornell Engineering Magazine. Way to go Ramya!

Mar 18, 2009

Christine has been awarded the best poster award at this year’s Bioexpo. Caroline, Dan, and Siddharth were co-authors on the poster. Congratulations to all!