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Cornell University

Fischbach Lab

We apply engineering principles to understand how tissue microenvironments influence cancer initiation, development, and therapy response.

Our Values

We value diverse ideas and identities and actively cultivate a community of inclusion and mutual respect both within our group and through interdisciplinary collaborations. This environment fosters scientific curiosity, creativity, and rigor to advance knowledge and the professional development of our lab members.

Recent Publications

Park S, Colville MJ, Paek JH, Shurer CR, Singh A, Secor EJ, Sailer CJ, Huang L, Kuo JC, Goudge MC, Su J, Kim M, DeLisa MP, Neelamegham S, Lammerding L, Zipfel WR, Fischbach C, Reesink HL, Paszek MJ. Immunoengineering can overcome the glycocalyx armour of cancer cells. Nature Materials. 2024.

Park S, Choi S, Shimpi AA, Estroff LA, Fischbach C, Paszek MJ. Collagen mineralization decreases NK cell-mediated cytotoxicity of breast cancer cells via increased glycocalyx thickness. Advanced Materials. 2024.

Recent News

Congratulations to Brittany Schutrum for defending her thesis examining the role of hyaluronic acid in regulating breast cancer invasion!

Congrats to Matt Whitman for successfully defending his thesis on the protective role of bone mineralization against breast cancer metastasis!